Gansu lyophilized Hib conjugate vaccine completes preclinical studies

    In order to further improve the localization of Hib vaccine and extend the effective period of the vaccine, in 2007, the Science and Technology Department of Gansu Province supported the Lanzhou Institute of Biological Products in the form of a major scientific and technological project to carry out “the development of freeze-dried Hib-conjugated vaccine”. So far, pre-clinical studies have been completed on lyophilized Hib conjugate vaccine in Gansu Province. The research progress is good and the expected technical indicators have been achieved.
    The Department of Science and Technology of Gansu Province introduced that the development of lyophilized Hib conjugate vaccine is an innovative development of the Hib vaccine dosage form. The successful development of this vaccine will play an important role in the prevention and control of related diseases.
    It is understood that Hib is short for Haemophilus influenzae type b and is mainly transmitted through airborne droplets. Children under 5 years of age, especially infants between 2 months and 2 years old, are easily infected and cause lower respiratory tract infections in infants and young children. The pathogenic bacteria of meningitis are also the first pathogens of respiratory diseases in children in China. Hib is very resistant to many antibiotics, so it is difficult to diagnose and treat them after infection.
    Hib vaccine can effectively prevent the diseases caused by Hib. However, due to the fact that the current Hib vaccine is a liquid formulation, it has a short shelf life, is not easy to store and transport, and is expensive, so China currently only uses Hib vaccine in some developed regions.

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